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Tricyclic antidepressants and specific anticonvulsants are the mainstay of scientific therapy for neuropathic agony (McQuay et al
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The hind paw withdrawal latency (s) to this stimulus was examined thrice at intervals of not below three min and also a mean calculated. The gadget has an automated cut-off at 21 s to avoid the chance of thermal personal injury towards the skin.
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Next this, unilateral L5 spinal nerve ligation was done. Seven times later on, sensory lionwin55 slot thresholds were reassessed and the development of allodynia to chilly and mechanical stimuli and hyperalgesia to some noxious thermal stimulus verified.